Neuro-pharmacology Practice Questions
20 free Neuro-pharmacology practice questions for the USMLE Step 1, each with the correct answer and a detailed explanation. Open any question below, or take the full set as an interactive quiz.
Questions
20 questions
All Neuro-pharmacology questions
- Q1. A patient with schizophrenia begins haloperidol therapy. Within days, he develops severe muscle stiffness and neck rigidity. Which adverse effect is most likel…
- Q2. A patient taking lithium for bipolar disorder begins experiencing tremor and confusion after starting hydrochlorothiazide. What is the most likely mechanism?
- Q3. A woman is prescribed fluoxetine for major depression. She is also taking a MAO inhibitor. What is the major risk of combining these medications?
- Q4. A patient with generalized anxiety disorder is started on buspirone. Which characteristic differentiates it from benzodiazepines?
- Q5. A patient taking levodopa for Parkinson disease develops hallucinations. Which drug can reduce this effect without worsening motor symptoms?
- Q6. A man with chronic pain is started on amitriptyline. What is the most likely adverse effect?
- Q7. A patient with epilepsy begins valproate therapy. Which serious adverse effect requires monitoring?
- Q8. A patient taking phenytoin presents with gingival hyperplasia. What mechanism explains this adverse effect?
- Q9. A patient with Alzheimer disease is started on donepezil. What is its mechanism?
- Q10. A patient receiving morphine develops respiratory depression. Which drug reverses this effect?
- Q11. A patient experiences acute anxiety during a flight and is prescribed medication with rapid onset. Which drug is appropriate?
- Q12. A patient with migraines is prescribed sumatriptan. What is its mechanism of action?
- Q13. A patient begins carbamazepine for trigeminal neuralgia. Which lab value should be monitored?
- Q14. A woman taking topiramate for seizures develops kidney stones. What mechanism contributes to this?
- Q15. A patient taking MAO inhibitors experiences hypertension after eating cheese and wine. What causes this reaction?
- Q16. A man with Parkinson disease is prescribed entacapone. What is its therapeutic mechanism?
- Q17. A patient with status epilepticus is treated with IV benzodiazepines. What receptor is primarily targeted?
- Q18. A patient treated with antipsychotics develops hyperprolactinemia. Which drug is most likely responsible?
- Q19. A man with opioid addiction begins methadone maintenance therapy. Which property makes methadone effective?
- Q20. A patient taking bupropion for depression asks why it does not cause sexual dysfunction like SSRIs. What is its mechanism?