Neuro-pharmacology · USMLE Step 1

A man with chronic pain is started on amitriptyline. What is the most likely adverse effect?

  1. Urinary retention
  2. Bradycardia
  3. Hypoglycemia
  4. Increased seizure threshold
Show answer and explanation

Correct answer: Urinary retention

TCAs have anticholinergic effects, including urinary retention, dry mouth, and constipation.

Difficulty: Medium Question 6 of 20

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