Neuro-pharmacology · USMLE Step 1

A patient with migraines is prescribed sumatriptan. What is its mechanism of action?

  1. β-adrenergic receptor blockade
  2. 5-HT1B/1D receptor agonism
  3. Calcium channel blockade
  4. D2 receptor antagonism
Show answer and explanation

Correct answer: 5-HT1B/1D receptor agonism

Sumatriptan activates 5-HT1B/1D receptors, causing vasoconstriction and reducing trigeminal pain signaling.

Difficulty: Medium Question 12 of 20

Practice all 20 Neuro-pharmacology questions

Keep practicing

More Neuro-pharmacology questions