Inflammation and repair Practice Questions
22 free Inflammation and repair practice questions for the USMLE Step 1, each with the correct answer and a detailed explanation. Open any question below, or take the full set as an interactive quiz.
Questions
22 questions
All Inflammation and repair questions
- Q1. Which of the following is one of the cardinal signs of acute inflammation?
- Q2. During the vascular phase of acute inflammation, which change occurs first?
- Q3. Which cell type is the predominant leukocyte in the first 24 hours of acute inflammation?
- Q4. What is the main function of macrophages during the wound-healing process after acute inflammation?
- Q5. Which of the following describes the correct sequence of wound healing phases under normal circumstances?
- Q6. Which extracellular matrix component helps form the initial scaffold for migrating cells during early wound healing?
- Q7. Which outcome of acute inflammation is most likely when the injurious agent is effectively removed and tissue architecture is intact?
- Q8. In chronic inflammation, which cell type becomes more predominant than neutrophils?
- Q9. Which mediator released during acute inflammation increases vascular permeability and contributes to swelling (tumor)?
- Q10. What characterizes ‘granulation tissue’ during the proliferative phase of tissue repair?
- Q11. Which factor is least likely to impair normal wound healing?
- Q12. Which type of inflammation is characterized by formation of epithelioid macrophages and multinucleated giant cells often surrounded by lymphocytes?
- Q13. Which event signals the beginning of the remodeling (maturation) phase of wound repair?
- Q14. What is the significance of Damage-Associated Molecular Patterns (DAMPs) in sterile inflammation?
- Q15. Which cytokines released by macrophages help drive the proliferative phase of wound healing by recruiting fibroblasts and promoting angiogenesis?
- Q16. When inflammation fails to resolve and persists, leading to tissue damage and attempts at repair concurrently, what is this condition called?
- Q17. Which mediator group derived from arachidonic acid plays a major role in inflammation (vasodilation, increased permeability, leukocyte chemotaxis)?
- Q18. Which of the following is a possible complication of wound healing when there is excessive fibroblast activity and collagen deposition beyond normal repair?
- Q19. Which statement best describes the difference between exudate and transudate in inflammation-related fluid accumulation?
- Q20. In an acute inflammatory exudate dominated by neutrophils and dead cell debris, what is the correct term for this type of inflammation?
- Q21. Which factor is most critical in determining whether injured tissue regenerates completely or scars by fibrosis during repair?
- Q22. During which phase of wound healing does neovascularization (angiogenesis) primarily occur?