Inflammation and repair · USMLE Step 1

What characterizes ‘granulation tissue’ during the proliferative phase of tissue repair?

  1. Dense collagen bundles with few cells
  2. New capillaries, fibroblasts, and loose ECM
  3. Keratinized stratified epithelium
  4. Necrotic debris and fibrin clot
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Correct answer: New capillaries, fibroblasts, and loose ECM

Granulation tissue is composed of newly formed capillaries (angiogenesis), proliferating fibroblasts, and a loose ECM — preparing the wound for scar formation.

Difficulty: Medium Question 10 of 22

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