Inflammation and repair · USMLE Step 1

What is the significance of Damage-Associated Molecular Patterns (DAMPs) in sterile inflammation?

  1. Bacterial endotoxins that trigger sepsis
  2. Signals that inhibit leukocyte migration
  3. Endogenous signals from injured cells that trigger inflammation
  4. Proteins that form the fibrin clot
Show answer and explanation

Correct answer: Endogenous signals from injured cells that trigger inflammation

DAMPs are endogenous molecules released from damaged cells that bind pattern-recognition receptors and trigger noninfectious inflammation.

Difficulty: Medium Question 14 of 22

Practice all 22 Inflammation and repair questions

Keep practicing

More Inflammation and repair questions