Inflammation and repair · USMLE Step 1

What is the main function of macrophages during the wound-healing process after acute inflammation?

  1. Trigger the initial vasodilation
  2. Phagocytose debris and release growth factors
  3. Form fibrin blood clots
  4. Produce new keratinocytes
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Correct answer: Phagocytose debris and release growth factors

Macrophages phagocytose debris and dead cells and secrete growth factors and cytokines that promote granulation tissue formation and progression to the proliferative phase.

Difficulty: Medium Question 4 of 22

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