Systemic Pathology by Organ · USMLE Step 1

In a patient with chronic hepatitis B infection, deposition of immune complexes in glomeruli may cause which renal pathology?

  1. Minimal change disease
  2. Membranous glomerulonephritis
  3. Focal segmental glomerulosclerosis
  4. Acute tubular necrosis
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Correct answer: Membranous glomerulonephritis

Hepatitis B-associated immune-complex deposition classically causes membranous glomerulonephritis, damaging the capillary walls and producing proteinuria or nephrotic syndrome.

Difficulty: Medium Question 7 of 19

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