Systemic Pathology by Organ · USMLE Step 1

Which pathological change in the lung is most characteristic of acute lobar pneumonia on gross examination?

  1. Dry, rubbery non-consolidated lobes
  2. Grey hepatization with consolidation
  3. Multiple large bullae and blebs
  4. Diffuse honeycomb fibrosis
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Correct answer: Grey hepatization with consolidation

In lobar pneumonia the alveoli fill with exudate and the lobe consolidates, becoming firm and liver-like (hepatization) — red early, then grey as cells and fibrin organize.

Difficulty: Medium Question 11 of 19

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