Systemic Pathology by Organ · USMLE Step 1

Which gross feature is suggestive of pulmonary tuberculosis in lungs obtained at autopsy?

  1. Diffuse consolidation of entire lobes
  2. Honeycomb fibrotic change throughout
  3. Upper-lobe cavitary caseous granulomas
  4. Multiple bullous spaces and blebs
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Correct answer: Upper-lobe cavitary caseous granulomas

Tuberculosis produces granulomas with caseous necrosis that can cavitate over time, characteristically in the upper lobes.

Difficulty: Medium Question 13 of 19

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