Systemic Pathology by Organ · USMLE Step 1

Which of the following is the most common glomerular pathology pattern seen in patients with chronic liver disease on renal biopsy studies?

  1. Minimal change disease
  2. IgA-dominant glomerulonephritis
  3. Focal segmental glomerulosclerosis
  4. Membranous nephropathy
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Correct answer: IgA-dominant glomerulonephritis

Chronic liver disease commonly produces IgA-dominant glomerular lesions with mesangial proliferation and immune-complex deposition (hepatic glomerulosclerosis).

Difficulty: Medium Question 12 of 19

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