Which factor does NOT directly influence the therapeutic index of a drug?
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Correct answer: Drug potency
Therapeutic index depends on the relationship between toxic and effective doses, not directly on potency. Potency refers to the amount of drug needed to produce an effect, whereas TI reflects safety. Thus, a drug may be potent but still have a wide or narrow TI.
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More Therapeutic Index questions
- A narrow therapeutic index implies that:
- Which statistical measures are typically used to calculate therapeutic index in animal studies?
- Warfarin requires regular INR monitoring primarily because it:
- A drug with a therapeutic index of 2 would be considered:
- Which term better reflects clinical safety in humans compared to the traditional therapeutic index?
- An increase in drug interactions that elevate plasma concentration would most significantly affect drugs with: