The therapeutic window of a drug refers to:
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Correct answer: The effective, non-toxic plasma drug concentration range
The therapeutic window is the range of plasma drug concentrations that produces therapeutic effects without causing significant toxicity. It lies between the minimum effective concentration (MEC) and the minimum toxic concentration (MTC). Drugs with narrow windows require careful monitoring.
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More Therapeutic Index questions
- Which factor does NOT directly influence the therapeutic index of a drug?
- A narrow therapeutic index implies that:
- Which statistical measures are typically used to calculate therapeutic index in animal studies?
- Warfarin requires regular INR monitoring primarily because it:
- A drug with a therapeutic index of 2 would be considered:
- Which term better reflects clinical safety in humans compared to the traditional therapeutic index?