A drug with a therapeutic index of 2 would be considered:
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Correct answer: Potentially dangerous
A therapeutic index of 2 means the lethal dose is only twice the effective dose. This small margin suggests a high risk of toxicity. Such drugs require careful dosing and monitoring.
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More Therapeutic Index questions
- Which term better reflects clinical safety in humans compared to the traditional therapeutic index?
- An increase in drug interactions that elevate plasma concentration would most significantly affect drugs with:
- Which of the following is LEAST likely to require therapeutic drug monitoring?
- The certain safety factor is calculated as:
- Which scenario would decrease the effective therapeutic index of a drug in a patient?
- In clinical practice, the therapeutic index is most relevant for drugs that: