A drug’s therapeutic index does NOT account for:
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Correct answer: Interindividual variability
Traditional therapeutic index calculations are based on median values and do not fully capture variability among individuals. Patient-specific factors can alter safety margins. Thus, TI may not reflect real-world clinical risk precisely.
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More Therapeutic Index questions
- Which change would widen the therapeutic index of a drug?
- In which phase of drug development is therapeutic index primarily determined?
- The therapeutic index (TI) of a drug is best defined as:
- A drug with a high therapeutic index is generally considered to be:
- Which of the following drugs is known to have a narrow therapeutic index?
- If the ED50 of a drug is 10 mg and the LD50 is 100 mg, the therapeutic index is: