Which of the following drugs is known to have a narrow therapeutic index?
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Correct answer: Digoxin
Digoxin has a narrow therapeutic index, meaning that the difference between therapeutic and toxic concentrations is small. Small changes in dose or plasma levels can result in toxicity. Careful monitoring of serum levels is often required.
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More Therapeutic Index questions
- If the ED50 of a drug is 10 mg and the LD50 is 100 mg, the therapeutic index is:
- The therapeutic window of a drug refers to:
- Which factor does NOT directly influence the therapeutic index of a drug?
- A narrow therapeutic index implies that:
- Which statistical measures are typically used to calculate therapeutic index in animal studies?
- Warfarin requires regular INR monitoring primarily because it: