Which NSAID is commonly used intravenously or intramuscularly for short-term management of moderate to severe acute pain, but is limited to 5 days of use due to high GI and renal toxicity?
Show answer and explanation
Correct answer: Ketorolac
Ketorolac is a very potent analgesic often used in post-operative settings. However, its significant inhibition of systemic prostaglandins leads to high risks of renal failure and GI bleeding, necessitating a strict 5-day limit on therapy.
Keep practicing
More NSAIDs questions
- Which of the following NSAIDs is a prodrug that is converted into its active sulfide metabolite in the liver, potentially sparing the stoma…
- NSAIDs can reduce the antihypertensive efficacy of ACE inhibitors primarily by which mechanism?
- Which condition is a classic contraindication for the use of NSAIDs due to the potential for 'triad' exacerbation (Samter's Triad)?
- What is the primary mechanism by which NSAIDs cause renal impairment, especially in dehydrated patients?
- Which of the following NSAIDs is often the drug of choice for the closure of a patent ductus arteriosus (PDA) in premature infants?
- Tinnitus and hearing loss are characteristic early signs of toxicity for which class of NSAIDs?