NSAIDs · Pharmacology

Tinnitus and hearing loss are characteristic early signs of toxicity for which class of NSAIDs?

  1. Propionic acid derivatives (Ibuprofen)
  2. Salicylates (Aspirin)
  3. Enolic acid derivatives (Piroxicam)
  4. Acetic acid derivatives (Diclofenac)
Show answer and explanation

Correct answer: Salicylates (Aspirin)

Salicylism is the term for mild aspirin toxicity, which frequently presents as tinnitus (ringing in the ears), dizziness, and hyperventilation. These symptoms are caused by direct effects on the cochlear hair cells and the respiratory center.

Difficulty: Medium Question 12 of 20

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