Which of the following NSAIDs is often the drug of choice for the closure of a patent ductus arteriosus (PDA) in premature infants?
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Correct answer: Indomethacin
PGE2 is responsible for keeping the ductus arteriosus open in utero. Indomethacin is a potent inhibitor of prostaglandin synthesis and is effectively used to promote the closure of the ductus in neonates.
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