Which of the following describes 'Hirano bodies' often seen in the hippocampus of Alzheimer patients?
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Correct answer: Eosinophilic, rod-like cytoplasmic inclusions of actin
Hirano bodies are bright eosinophilic, paracrystalline, rod-like inclusions found primarily in the CA1 pyramidal neurons of the hippocampus. They are composed mainly of actin and actin-associated proteins.
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