Amyotrophic Lateral Sclerosis (ALS) involves the degeneration of which of the following?
Show answer and explanation
Correct answer: Both upper and lower motor neurons
ALS is a progressive disorder involving the loss of upper motor neurons in the cerebral cortex and lower motor neurons in the spinal cord and brainstem. This leads to a combination of spasticity and muscle atrophy.
Keep practicing
More Neurodegenerative Disorders questions
- Which of the following is a characteristic histological finding in the brains of patients with Prion diseases like Creutzfeldt-Jakob Diseas…
- A 65-year-old patient presents with rapidly progressive dementia, visual hallucinations, and parkinsonian features. What is the most likely…
- Multiple System Atrophy (MSA) is characterized by alpha-synuclein inclusions found primarily in which cell type?
- Which genetic mutation is the most common cause of familial Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD)?
- The 'hydrocephalus ex vacuo' seen in advanced Alzheimer disease is a result of:
- Which protein accumulates in the spinal cord of nearly 95% of patients with Amyotrophic Lateral Sclerosis (ALS)?