Autoimmune Diseases · Pathology

Which histological feature is characteristic of the 'Libman-Sacks' endocarditis seen in SLE?

  1. Large, irregular friable vegetations along the free valve edges
  2. Small sterile vegetations on both valve leaflet surfaces
  3. Perforation of the mitral valve cusp
  4. Calcific stenosis of the aortic valve
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Correct answer: Small sterile vegetations on both valve leaflet surfaces

Libman-Sacks endocarditis involves small, verrucous, non-bacterial vegetations. They are unique because they can develop on the undersurfaces of the valves, the chordae tendineae, or the endocardial surfaces.

Difficulty: Medium Question 6 of 20

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