Autoimmune Diseases · Pathology

Which of the following is a component of the CREST syndrome variant of Limited Scleroderma?

  1. Erythema marginatum
  2. Hepatosplenomegaly
  3. Esophageal dysmotility
  4. Diffuse glomerulonephritis
Show answer and explanation

Correct answer: Esophageal dysmotility

CREST stands for Calcinosis, Raynaud phenomenon, Esophageal dysmotility, Sclerodactyly, and Telangiectasia. Esophageal dysfunction results from submucosal fibrosis and atrophy of the muscularis propria.

Difficulty: Medium Question 8 of 20

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