Adverse Drug Reactions and Interactions · USMLE Step 1

Which of the following is true about drug interactions involving food or beverages?

  1. They reliably improve a drug's effectiveness
  2. They interfere solely with drug absorption
  3. They may change drug metabolism or efficacy
  4. They pose little risk of drug toxicity
Show answer and explanation

Correct answer: They may change drug metabolism or efficacy

Food or beverages (e.g., grapefruit juice) can inhibit metabolizing enzymes or transporters and thereby alter drug exposure, leading to increased toxicity or reduced efficacy.

Difficulty: Medium Question 16 of 19

Practice all 19 Adverse Drug Reactions and Interactions questions

Keep practicing

More Adverse Drug Reactions and Interactions questions