Which of the following best differentiates benign tumors from malignant neoplasms on gross and microscopic pathology?
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Correct answer: Benign tumors stay localized and differentiated; malignant invade, metastasize, and show pleomorphism
Benign neoplasms generally remain localized, grow expansively without invasion, are well differentiated; malignant neoplasms invade surrounding tissue, may metastasize, and show cellular atypia and pleomorphism.
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