The transition from a pre-malignant lesion to invasive cancer typically requires which additional capability acquired by tumor cells?
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Correct answer: Ability to invade the basement membrane and metastasize
To progress from a premalignant lesion to invasive cancer, cells must gain the ability to invade through the basement membrane, invade surrounding tissue, and potentially metastasize.
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More Neoplasia and Cancer Biology questions
- Which classification system describes the extent of spread of a malignant tumor including size, lymph node involvement, and metastasis?
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- Which phenomenon describes neoplastic cells acquiring the ability to divide indefinitely, avoiding normal replicative senescence?
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