Neoplasia and Cancer Biology · USMLE Step 1

Which classification system describes the extent of spread of a malignant tumor including size, lymph node involvement, and metastasis?

  1. Grading
  2. Staging (TNM)
  3. Differentiation score
  4. Angiogenesis index
Show answer and explanation

Correct answer: Staging (TNM)

Staging (commonly TNM) assesses the tumor’s size/extent (T), nodal involvement (N), and presence of distant metastasis (M), which helps guide prognosis and therapy.

Difficulty: Medium Question 10 of 20

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