Which enzyme in glycolysis is regulated both by allosteric effectors and by hormonal (covalent) modification in liver tissue?
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Correct answer: Pyruvate kinase
Pyruvate kinase in the liver is allosterically activated by fructose-1,6-bisphosphate and inhibited by ATP/alanine, and is also regulated via phosphorylation by hormonal signals (e.g., glucagon) — integrating metabolic and endocrine control.
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More Metabolic Pathways and Regulation questions
- Which enzyme catalyzes the rate-limiting step of glycolysis and is strongly regulated by cellular energy status?
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