Which three enzymes catalyze the essentially irreversible, regulatory steps of glycolysis?
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Correct answer: Hexokinase, PFK-1, Pyruvate kinase
The irreversible, regulatory steps in glycolysis are catalyzed by hexokinase (or glucokinase), PFK-1, and pyruvate kinase — these steps have large negative ΔG and allow control of glycolytic flux.
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