Screening and Diagnostic Test Validity · USMLE Step 1

A confirmatory test for HIV is chosen because it has very high specificity. What is the advantage of this?

  1. High ability to rule out disease (SnNout)
  2. High ability to rule in disease (SpPin)
  3. Increased PPV regardless of prevalence
  4. Reduced false-negative rate
Show answer and explanation

Correct answer: High ability to rule in disease (SpPin)

A test with high specificity is good at ruling in a disease when positive (SpPin). It reduces false positives, making it useful for confirmatory testing.

Difficulty: Medium Question 6 of 20

Practice all 20 Screening and Diagnostic Test Validity questions

Keep practicing

More Screening and Diagnostic Test Validity questions