Screening and Diagnostic Test Validity · USMLE Step 1

A test used for initial screening for HIV has very high sensitivity. Why is this desirable?

  1. It minimizes false negatives
  2. It minimizes false positives
  3. It maximizes PPV
  4. It decreases disease prevalence
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Correct answer: It minimizes false negatives

A highly sensitive test correctly identifies most people with the disease, minimizing false negatives. This is crucial for screening to avoid missing cases.

Difficulty: Medium Question 5 of 20

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