Screening and Diagnostic Test Validity · USMLE Step 1

A new test has the following characteristics: sensitivity 70% and specificity 90%. What can be inferred?

  1. It will miss many true positive cases
  2. It has a high false-positive rate
  3. It identifies almost all true positives
  4. It has poor accuracy overall
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Correct answer: It will miss many true positive cases

A sensitivity of 70% means the test will miss 30% of true cases (false negatives). Specificity is relatively high, but sensitivity is moderate.

Difficulty: Medium Question 7 of 20

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