Screening and Diagnostic Test Validity · USMLE Step 1

A clinician wants to minimize missing a case of meningitis in infants. Which type of test should be used first?

  1. A highly specific test
  2. A highly sensitive test
  3. A moderately accurate test
  4. A test with high PPV
Show answer and explanation

Correct answer: A highly sensitive test

High sensitivity is crucial for screening severe diseases because missing cases carries serious risk. A sensitive test minimizes false negatives.

Difficulty: Medium Question 16 of 20

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