Screening and Diagnostic Test Validity · USMLE Step 1

A study evaluates a new test and finds that it overestimates disease in one demographic group but not others. What bias is this?

  1. Lead-time bias
  2. Length-time bias
  3. Detection bias
  4. Spectrum bias
Show answer and explanation

Correct answer: Spectrum bias

Spectrum bias occurs when test performance varies across different populations or disease severities. The test behaves differently depending on the group.

Difficulty: Medium Question 18 of 20

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