Screening and Diagnostic Test Validity · USMLE Step 1

A test detects a disease earlier but does not change the time of death. What bias falsely inflates survival time?

  1. Length-time bias
  2. Lead-time bias
  3. Attrition bias
  4. Recall bias
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Correct answer: Lead-time bias

Lead-time bias occurs when earlier detection increases the time between diagnosis and death without improving actual survival. This creates the illusion of extended survival.

Difficulty: Medium Question 20 of 20

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