Screening and Diagnostic Test Validity · USMLE Step 1

A diagnostic test has a specificity of 98%. What does this indicate about the test?

  1. It correctly identifies 98% of people who have the disease
  2. It has a high false-negative rate
  3. It correctly identifies 98% of people who do NOT have the disease
  4. It reduces the prevalence of disease
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Correct answer: It correctly identifies 98% of people who do NOT have the disease

Specificity describes the probability of correctly identifying individuals who do not have the disease. A specificity of 98% means the test has a low false-positive rate.

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