Absorption mechanisms · Physiology

Bile salts are essential for lipid digestion, but they are not absorbed with the fats in the upper small intestine. Where and how are they primarily recovered?

  1. Simple diffusion in the duodenum
  2. Active transport in the terminal ileum
  3. Facilitated diffusion in the ascending colon
  4. Receptor-mediated endocytosis in the jejunum
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Correct answer: Active transport in the terminal ileum

The majority of bile salts are reabsorbed via the Apical Sodium-dependent Bile acid Transporter (ASBT) in the terminal ileum. This process is the critical step in the enterohepatic circulation.

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