Absorption mechanisms · Physiology

A patient with a resection of the distal 50 cm of the ileum is most likely to develop which of the following conditions?

  1. Iron deficiency anemia with marked glossitis
  2. Megaloblastic anemia with steatorrhea
  3. Progressive osmotic glucose intolerance
  4. Symptomatic refractory hypercalcemia
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Correct answer: Megaloblastic anemia with steatorrhea

The terminal ileum is the exclusive site for Vitamin B12 absorption and the primary site for bile salt reabsorption. Loss of this segment leads to B12 deficiency (megaloblastic anemia) and impaired fat emulsification (steatorrhea) due to a depleted bile salt pool.

Difficulty: Medium Question 36 of 40

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