Calcium absorption is regulated by 1,25-dihydroxyvitamin D3. What is the role of calbindin in this process?
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Correct answer: It shuttles calcium across the cytosol to the basolateral membrane
Calbindin is an intracellular binding protein that prevents free calcium levels from rising too high inside the enterocyte while facilitating its movement to the basolateral side. Its synthesis is directly stimulated by active Vitamin D.
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