Which form of dietary folate is the most common, and how is it modified prior to absorption?
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Correct answer: Polyglutamate; trimmed to monoglutamate at the brush border
Dietary folate mostly exists as polyglutamates. The enzyme folate conjugase on the brush border must strip the extra glutamate residues to form monoglutamate, which is the only form transported into the enterocyte.
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