The presence of the HLA-B*15:02 allele is a strong predictor of Stevens-Johnson Syndrome (SJS) in patients taking which medication?
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Correct answer: Carbamazepine
HLA-B*15:02 is highly associated with carbamazepine-induced SJS and toxic epidermal necrolysis, particularly in populations of Han Chinese or Southeast Asian descent. Screening is recommended before initiating therapy in high-risk groups.
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