The '3 C's'—Coma, Convulsions, and Cardiotoxicity—are classic signs of overdose for which class of antidepressants?
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Correct answer: Tricyclic antidepressants
Tricyclic antidepressants are highly toxic in overdose. Their cardiotoxicity is primarily due to the blockade of fast sodium channels in the heart, leading to QRS prolongation, arrhythmias, and death.
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