Which tricyclic antidepressant (TCA) is frequently used in the management of obsessive-compulsive disorder (OCD) due to its high selectivity for serotonin reuptake inhibition?
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Correct answer: Clomipramine
Clomipramine is a TCA with a unique chemical structure that makes it much more potent at inhibiting serotonin reuptake than other TCAs. While SSRIs are now first-line, clomipramine remains a gold-standard treatment for refractory OCD.
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