Sulfamethoxazole is typically combined with Trimethoprim in what ratio by weight in a standard tablet?
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Correct answer: 5:1
The standard ratio is 5 parts Sulfamethoxazole to 1 part Trimethoprim (e.g., 400mg/80mg). This ratio is designed to achieve a 20:1 ratio of the drugs in the plasma, which is optimal for synergistic antimicrobial effects.
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