Sulfadiazine combined with Pyrimethamine is the first-line regimen for the treatment of which condition?
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Correct answer: Cerebral toxoplasmosis
The combination of sulfadiazine and pyrimethamine is the gold standard for treating toxoplasmosis, particularly in AIDS patients. Leucovorin (folinic acid) is typically added to protect the patient's bone marrow from folic acid deficiency.
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More Sulfonamides questions
- Which of the following describes the primary mechanism of action of sulfonamides?
- Why are sulfonamides bacteriostatic against many bacteria but relatively non-toxic to mammalian cells?
- Which enzyme is targeted by Trimethoprim, the agent frequently combined with Sulfamethoxazole?
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- Which sulfonamide is specifically used topically to prevent infections in patients with extensive second- and third-degree burns?
- What is the primary mechanism of resistance developed by bacteria against sulfonamides?