What is the primary mechanism of action of beta-lactam antibiotics?
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Correct answer: Binding penicillin-binding proteins to block cell wall synthesis
Beta-lactams act as structural analogs of the D-Ala-D-Ala substrate. They covalently bind to PBPs, which are enzymes responsible for cross-linking peptidoglycan chains, leading to bacterial cell lysis.
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More Beta-Lactam Antibiotics questions
- Which of the following beta-lactamase inhibitors is commonly paired with Piperacillin to extend its spectrum of activity?
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