NSAIDs · Pharmacology

Misoprostol is sometimes co-administered with NSAIDs to prevent which adverse effect?

  1. Renal papillary necrosis
  2. NSAID-induced gastric ulcers
  3. Platelet dysfunction
  4. Hepatic encephalopathy
Show answer and explanation

Correct answer: NSAID-induced gastric ulcers

Misoprostol is a synthetic prostaglandin E1 analog. It replaces the protective prostaglandins in the stomach that are lost during NSAID therapy, thereby stimulating mucus and bicarbonate secretion and inhibiting acid production.

Difficulty: Medium Question 13 of 20

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