NSAIDs · Pharmacology

Which property of Naproxen makes it distinct from Ibuprofen in terms of patient compliance?

  1. It is only available as an injection
  2. It has a longer half-life allowing for twice-daily dosing
  3. It does not cause any GI distress
  4. It is a selective COX-2 inhibitor
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Correct answer: It has a longer half-life allowing for twice-daily dosing

Naproxen has a longer half-life (approx. 12-15 hours) compared to ibuprofen (approx. 2 hours). This allows for more convenient twice-daily dosing, whereas ibuprofen typically requires dosing every 4-6 hours for anti-inflammatory effects.

Difficulty: Medium Question 14 of 20

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