Which neurodegenerative condition is specifically associated with the loss of dopaminergic neurons in the locus coeruleus and substantia nigra?
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Correct answer: Parkinson disease
Parkinson disease is defined by the loss of pigmented (catecholaminergic) neurons in the substantia nigra pars compacta and the locus coeruleus. This loss leads to the dopamine deficiency that causes motor symptoms.
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