Progressive Supranuclear Palsy (PSP) is a tauopathy that classically presents with which clinical sign?
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Correct answer: Vertical gaze palsy
PSP is a 4R-tauopathy characterized by vertical supranuclear gaze palsy, axial rigidity, and frequent falls. Pathologically, it shows globose neurofibrillary tangles in the brainstem and basal ganglia.
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